What it is: Indole-3-carbinol (I3C) is a plant-derived compound produced when cruciferous vegetables such as broccoli, Brussels sprouts, and cabbage are chopped or chewed. It is classified as a phytochemical with bioactive properties.
What it does: I3C supports the body’s natural estrogen metabolism pathways, promoting the breakdown of estrogen into less active forms. It is researched for supporting healthy cellular functions, especially in hormone-sensitive tissues.
How it is used: Supplements containing I3C are commonly used for hormonal balance, reproductive system wellness, and support of healthy breast, prostate, and cervical cells.
Natural sources and supplement forms: I3C occurs naturally in cruciferous vegetables but is also available in standardized powder or capsule supplement form, often noted as a purified single compound.
Why it appears in supplement formulas: Brands include I3C to help the body maintain balanced estrogen metabolism and to support normal cell growth, especially in tissues influenced by hormones.
What to know before use: High doses of I3C may cause digestive upset in some people or interact with hormone-related medications. Consult a healthcare provider if you have hormone-sensitive conditions or are on related medications.
Ingredient guide
