What it does: This amino acid supports the production of nitric oxide, a molecule that relaxes blood vessels and promotes better circulation. It is also involved in helping the body manage waste products from metabolism.
How it is used: L-Citrulline is commonly used in pre-workout and endurance supplements to support exercise performance, reduce muscle fatigue, and aid post-exercise muscle recovery.
Natural sources and supplement forms: Watermelon is particularly rich in L-citrulline; smaller amounts are found in other melons and some vegetables. Supplement forms include L-citrulline powder, capsules, and L-citrulline malate, which pairs the amino acid with malic acid for enhanced bioavailability.
Why it appears in supplement formulas: L-Citrulline is included to help support stamina, boost circulation, and improve athletic performance by increasing nitric oxide availability in the body.
What to know before use: L-Citrulline is considered safe for most healthy adults, but those taking medication for blood pressure or heart conditions should consult a healthcare professional before use.
L-Citrulline: Watermelon’s Secret Amino Acid
L-Citrulline gets its name from Citrullus, the Latin word for watermelon, because it was first discovered in watermelon pulp over a century ago. This non-essential amino acid is a key player in the body’s urea cycle, helping convert ammonia to urea for excretion. Naturally present in watermelon, L-citrulline is often used in supplements to support natural metabolic pathways.
