What it does: PQQ is known for supporting the formation of new mitochondria (mitochondrial biogenesis), aiding the body’s ability to generate energy, and protecting brain and nerve cells from oxidative damage. It is studied for its connection to cognitive support and cellular resilience.
How it is used: Supplement users often take PQQ to promote sustained energy, enhance mental clarity, and support healthy aging and brain performance.
Natural sources and supplement forms: PQQ occurs naturally in fermented foods like natto, and in small amounts in parsley, green peppers, potatoes, and kiwi. In supplements, it is typically available as purified or synthesized PQQ disodium salt for precision in dosing.
Why it appears in supplement formulas: PQQ is included for its unique ability to promote mitochondrial health, improve cellular energy production, and support cognitive function—appealing to those seeking improved physical and mental vitality.
What to know before use: PQQ is generally well tolerated, but due to limited research on long-term use, those with health conditions or on medications should check with their healthcare provider before starting supplementation.
PQQ: A Rare Nutrient Found in Fermented Foods
Pyrroloquinoline quinone (PQQ) is a nutrient and antioxidant that naturally occurs in small amounts in foods such as kiwi, parsley, green peppers, and especially in fermented foods like natto (fermented soybeans). Its unique structure helps it participate in cellular processes related to energy, which is why it's often included in supplement formulas designed to support cellular function.
