Ingredient Guide

PQQ

PQQ (pyrroloquinoline quinone) is a bioactive, vitamin-like compound that helps protect cells from oxidative stress and encourages the growth of new mitochondria, which are the cell's energy centers. People use PQQ supplements to support daily energy, mental sharpness, and overall cellular health.

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PQQ

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Ingredient guide

PQQ

What it is: PQQ, or pyrroloquinoline quinone, is a redox-active micronutrient found in small amounts in certain foods and plants. It acts as a powerful antioxidant and is considered a cofactor for specific enzymes that help maintain cellular function and energy.
What it does: PQQ is known for supporting the formation of new mitochondria (mitochondrial biogenesis), aiding the body’s ability to generate energy, and protecting brain and nerve cells from oxidative damage. It is studied for its connection to cognitive support and cellular resilience.
How it is used: Supplement users often take PQQ to promote sustained energy, enhance mental clarity, and support healthy aging and brain performance.
Natural sources and supplement forms: PQQ occurs naturally in fermented foods like natto, and in small amounts in parsley, green peppers, potatoes, and kiwi. In supplements, it is typically available as purified or synthesized PQQ disodium salt for precision in dosing.
Why it appears in supplement formulas: PQQ is included for its unique ability to promote mitochondrial health, improve cellular energy production, and support cognitive function—appealing to those seeking improved physical and mental vitality.
What to know before use: PQQ is generally well tolerated, but due to limited research on long-term use, those with health conditions or on medications should check with their healthcare provider before starting supplementation.
Interesting Fact

PQQ: A Rare Nutrient Found in Fermented Foods

Pyrroloquinoline quinone (PQQ) is a nutrient and antioxidant that naturally occurs in small amounts in foods such as kiwi, parsley, green peppers, and especially in fermented foods like natto (fermented soybeans). Its unique structure helps it participate in cellular processes related to energy, which is why it's often included in supplement formulas designed to support cellular function.

FAQ

Frequently Asked Questions About PQQ

What does PQQ do in the body?

PQQ (pyrroloquinoline quinone) is involved in supporting mitochondrial function and cellular energy metabolism. As a redox-active compound, it assists antioxidant defenses and helps protect cells from oxidative stress. PQQ is being studied for its potential to support cognitive performance and healthy aging by promoting efficient cell energy production and protecting neural structures.

What foods are natural sources of PQQ?

Natural sources of PQQ include fermented soy products such as natto, as well as kiwi, parsley, green peppers, and some other fruits and vegetables. However, the amounts found in foods are very small compared to supplement doses, which is why most supplements use a purified, synthesized form of PQQ for more concentrated effects.

How is PQQ different from CoQ10 in supplements?

PQQ and CoQ10 are both involved in mitochondrial health, but they have different structures and roles. PQQ functions as a redox cofactor and supports the creation of new mitochondria, while CoQ10 is vital for mitochondrial energy production and acts as an electron carrier. Some formulas pair them together for combined mitochondrial support.

Is PQQ safe to take with other supplements or medications?

PQQ is generally well tolerated in supplement form, but because it affects cellular energy pathways, it’s best to consult a healthcare professional before combining it with other supplements or medications, especially those that target mitochondrial function or antioxidant pathways. People with underlying health conditions should seek professional guidance before use.






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